The Central Board of Indirect Taxes & Customs vide notification dated 25.07.2022 has issued Clarification on Electro-Chemiluminescence Immunoassay kits. It is clarified that Chemiluminescence immunoassay (CLIA) is a widely used detection method which combines the highly-sensitive chemiluminescence assay with highly-specific Immune response and affinity of antibodies. In CLIA diagnostic kits, chemiluminescence technique is combined with immunochemical reactions. CLIA Kits are designed to detect the chemiluminescence reactions. In CLIA the label, i.e. the true “indicator” of the analytic reaction, is a luminescent molecule.
CLIA have different label systems which shall include:
- Label Chemical Directly Involved in the Light Emission Reaction
- Enzyme Catalyzed Light Emission Reaction
- Redox Reaction Mediated Light Emission Reaction (ECLIA).
