Ministry of Science & Technology on May 08, 2023 has announced that Newly synthesized biocompatible drug delivery system combined with anti-inflammatory drugs is developed, which brings potential solution for rheumatoid arthritis.
Scientists from Institute of Nano Science and Technology (INST), Mohali, an autonomous institute of Department of Science and Technology, explored the potential of the anti-inflammatory FDA-approved drug 9-aminoacridine (9AA) and the natural compound caffeic acid (CA), generally found in coffee or wine (reported to possess significant anti-arthritic potential) conjugated to nano micelles, an amphiphilic molecule that forms spherical structure when immersed in water, for the treatment of RA.
This drug delivery system is simple, cost-effective, safe, and has significant translational potential. The nano-formulation so far tested on rats and published in ACS Nano may bring long-term relief for numerous RA patients in the future by suppressing the disease severity of Rheumatoid arthritis.
